Scream 4 sees Sidney Prescott returning to Woodsboro, ten years after the original killings, to promote her new book. However, the peaceful reunion is shattered when a new Ghostface killer emerges, targeting a new generation of teens. As Sidney, Gale, and Dewey work together to uncover the killer’s identity, they confront fresh twists on the classic slasher formula, exploring themes of legacy, the impact of social media, and the dangers of fame. The film blends horror, suspense, and self-aware humor, keeping the franchise's trademark twists and suspense alive.

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